Treatment of toenail onychomycosis with 2% butenafine and 5% Melaleuca alternifolia (tea tree) oil in cream
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Treatment of toenail onychomycosis with 2% butenafine and 5% Melaleuca alternifolia (tea tree) oil in cream.
The prevalence of onychomycosis, a superficial fungal infection that destroys the entire nail unit, is rising, with no satisfactory cure. The objective of this randomized, double-blind, placebo-controlled study was to examine the clinical efficacy and tolerability of 2% butenafine hydrochloride and 5% Melaleuca alternifolia oil incorporated in a cream to manage toenail onychomycosis in a cohort...
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The in vitro activity of Melaleuca alternifolia (tea tree) oil against dermatophytes (n = 106) and filamentous fungi (n = 78) was determined. Tea tree oil MICs for all fungi ranged from 0.004% to 0.25% and minimum fungicidal concentrations (MFCs) ranged from <0.03% to 8.0%. Time-kill experiments with 1-4 x MFC demonstrated that three of the four test organisms were still detected after 8 h of t...
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5. Enzinger FH, Weiss SW: 1988, Soft tissue tumors, pp. 781– 815. CV Mosby, St. Louis, MO. 6. Erlandson RA: 1985, Peripheral nerve sheath tumors. Ultrastruct Pathol 9:113–122. 7. Johnston RC, Anderson WI, Luther PB, et al.: 1988, Multicentric schwannoma in a mature Holstein cow. Vet Rec 123: 649–650. 8. Jubb KVF, Huxtable CR: 1993, The nervous system. In: Pathology of domestic animals, ed. Jubb...
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Complementary and alternative medicines such as tea tree (melaleuca) oil have become increasingly popular in recent decades. This essential oil has been used for almost 100 years in Australia but is now available worldwide both as neat oil and as an active component in an array of products. The primary uses of tea tree oil have historically capitalized on the antiseptic and anti-inflammatory ac...
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ژورنال
عنوان ژورنال: Tropical Medicine and International Health
سال: 1999
ISSN: 1360-2276,1365-3156
DOI: 10.1046/j.1365-3156.1999.00396.x